Glucagon
 
Presentation
• 1mg (IU) in 1ml Hypokit
Pharmacology
• A hormone normally secreted by the pancreas
Actions
• Causes an increase in blood glucose concentration by converting stored liver glycogen to glucose
Metabolism
• Mainly by the liver, also by the kidneys and in the plasma
Primary Emergency Indications
• Diabetic hypoglycaemia (BGL <4mmol/l) in Pts with an altered conscious state who are unable to self-administer oral glucose Adult Paed
Contraindications
• Nil of signifcance in the above indication
Precautions
• Nil of signifcance in the above indication
Route of Administration
• IM
Side Effects
• Nausea and vomiting (rare)
Special Notes
• Not all Pts will respond to Glucagon, for example those with inadequate glycogen storage in the liver – alcoholics, malnourishment.
Therapeutic Effect
IM     
Onset:
3-5min
Peak:
Duration:
12-25min