Metaraminol |
Presentation |
• 10mg in 1ml amp | ||||||||||||
Pharmacology |
• A synthetic adrenergic stimulant with primarily Alpha effects | ||||||||||||
Actions |
• Causes peripheral vasoconstriction (α) - Increases myocardial contractility ( - Increases the irritability of the ventricles ( |
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Metabolism |
• By monoamine oxidase and other enzymes in blood, liver and around nerve endings and excreted by the kidneys | ||||||||||||
Primary Emergency Indications |
• SVT associated with inadequate perfusion and a BP <100 Adult • Inadequate to extremely poor perfusion secondary to the combination of Sildenafil "Viagra", Vardenafil "Levitra" or Tadalafil "Cialis" and Glyceryl Trinitrate administration Adult |
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Contraindications |
• Nil in the above setting | ||||||||||||
Precautions |
• Causes tissue necrosis, avoid leakage of the drug into the tissues • Do not raise blood pressure over 90-100 systolic |
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Route of Administration |
• IV | ||||||||||||
Side Effects |
• Sinus tachycardia • Ventricular arrhythmias • Hypertension |
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Special Notes |
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Therapeutic Effect |
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| Reference | Dilutions Metaraminol IV |