Sodium Bicarbonate 8.4% |
Presentation |
• 50ml prepared syringe (Sodium Bicarbonate 8.4%) | ||||||||||||
Pharmacology |
• A hypertonic crystalloid solution • Contains sodium and bicarbonate ions in a solution of high pH |
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Actions |
• Raises pH | ||||||||||||
Metabolism |
• Sodium: Excreted by the kidneys • Bicarbonate: Excreted by the kidneys as bicarbonate ion, and by the lungs as carbon dioxide |
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Primary Emergency Indications |
• To reduce metabolic acidosis during cardiopulmonary resuscitation after 15 minutes of
Ambulance personnel CPR Adult Paed • Symptomatic Tricyclic Antidepressant Overdose Adult Paed |
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Contraindications |
• Nil of signifcance in the above indications | ||||||||||||
Precautions |
• Administration of Sodium Bicarbonate 8.4% must be accompanied by effective
ventilation and External Cardiac Compression if required • Since Sodium Bicarbonate 8.4% causes tissue necrosis, care must be taken to avoid leakage of the drug into the tissues • Because of the high pH of this solution do not mix or fush any other drug or solution with Sodium Bicarbonate 8.4% |
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Route of Administration |
• IV | ||||||||||||
Side Effects |
• Sodium overload may provoke pulmonary oedema • Excessive dosage of Sodium Bicarbonate 8.4%, especially without adequate ventilation and circulation may cause an intracellular acidosis. |
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Special Notes |
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Therapeutic Effect |
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