Oxytocin (Syntocinon) |
Presentation |
• 10 units (iu) in 1 ml ampoule | ||||||||||||
Pharmacology |
• A synthetic oxytocic | ||||||||||||
Actions |
• Stimulates smooth muscle of the uterus producing contractions | ||||||||||||
Metabolism |
• By the liver Excreted by the kidneys | ||||||||||||
Primary Emergency Indications |
• Primary post partum haemorrhage Obst | ||||||||||||
| • Previous Hypersensitivity • Severe toxaemia (pre-eclampsia) • Ensure multiple pregnancy excluded before drug administration • Cord prolapse |
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Precautions |
• If given IV may cause transient hypotension • Concurrent use with Methoxyflurane may cause hypotension |
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Route of Administration |
• IM | ||||||||||||
Side Effects |
• Uncommon via IM route: - Tachycardia - Bradycardia - Nausea |
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Special Notes |
• Concomitant use with prostaglandins (Misoprostol) may potentiate uterotonic effect • Must be stored between 2 to 8°C |
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Therapeutic Effect |
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